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- Diabetes Mellitus 0%
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- Question 1 of 50
1. Question
1 points1 which of the following condition is characterized by absolute insulin deficiency
I Type 1 diabetes mellitus (T1DM)
II Type 2 diabetes mellitus (T2DM)
III Type 1 diabetes mellitus (T1DM) and Type 2 diabetes mellitus (T2DM)CorrectIncorrect - Question 2 of 50
2. Question
1 points2 which of the following are the characteristics of Type 1 diabetes mellitus (T1DM)
I absolute insulin deficiency
II autoimmune destruction of the beta -cells of the islets of Langerhans
III requires insulin therapyCorrectIncorrect - Question 3 of 50
3. Question
1 points3 which of the following are the characteristics of Type 2 diabetes mellitus (T2DM)
I most common form of DM
II autoantibodies are absent in T2DM.
III obesity is a risk factorCorrectIncorrect - Question 4 of 50
4. Question
1 points4 which of the following is correct about Gestational diabetes mellitus
I elevated plasma glucose during pregnancy
II elevated plasma glucose during and after pregnancy
III elevated plasma glucose before pregnancyCorrectIncorrect - Question 5 of 50
5. Question
1 points5 which of the following can cause diabetes mellitus
I glucocorticoids
II antipsychotics
III statinsCorrectIncorrect - Question 6 of 50
6. Question
1 points6 normal glucose regulation involves which of the following
I insulin
II incretin hormones
III amylin.CorrectIncorrect - Question 7 of 50
7. Question
1 points7 which of the following are the fuctions of insulin
I Promotes the cellular uptake of plasma glucose
II Inhibits production of glucose from liver, muscle glycogen, or amino acids
III Stimulates conversion of glucose into glycogen and fatCorrectIncorrect - Question 8 of 50
8. Question
1 points8 what are the Counterregulatory hormones which increases blood glucose
I Glucagon
II Cortisol
IIITSHCorrectIncorrect - Question 9 of 50
9. Question
1 points9 which are the Incretin hormones secreated by intestine
I Glucagon
II gastric inhibitory peptide (GIP)
III glucagon-like peptide-1 (GLP-1)CorrectIncorrect - Question 10 of 50
10. Question
1 points10 which of the following are the actions of glucagon-like peptide-1 (GLP-1)
I Slows gastric emptying
II Increases glucose-dependent insulin secretion
III Suppresses appetiteCorrectIncorrect - Question 11 of 50
11. Question
1 points11 what are the symptoms if type 2 diabetes
I Polyuria, polydipsia, polyphagia
II weight loss, Blurred vision
III Lower-extremity paresthesiasCorrectIncorrect - Question 12 of 50
12. Question
1 points12 Diagnostic criteria by the American Diabetes Association (ADA) include the following
I A fasting plasma glucose (FPG) level of 126 mg/dL (7.0 mmol/L) or higher
II A 2-hour plasma glucose level of 200 mg/dL (11.1 mmol/L) or higher during a 75-g oral glucose tolerance test (OGTT)
III A random plasma glucose of 200 mg/dL (11.1 mmol/L) or higherCorrectIncorrect - Question 13 of 50
13. Question
1 points13 Approaches to prevention of diabetic complications include the following
I HbA1c every 3-6 months
II Yearly dilated eye examinations
III Foot examinations at each visitCorrectIncorrect - Question 14 of 50
14. Question
1 points14 Metformin comes under which of the following catagory
I Biguanides
II Sulfonylureas
III Meglitinide derivativesCorrectIncorrect - Question 15 of 50
15. Question
1 points15 Metformin works by which of the following mechanism
I decreasing hepatic gluconeogenesis production
II decreases intestinal absorption of glucose
III improves insulin sensitivity by increasing peripheral glucose uptake and utilizationCorrectIncorrect - Question 16 of 50
16. Question
1 points16 which of the following are true about metformin
I rarely causes hypoglycemia.
II facilitates modest weight loss
III causes hepatic toxicityCorrectIncorrect - Question 17 of 50
17. Question
1 points17 which of the following are Sulfonylureas
I glyburide,
II glipizide,
III glimepirideCorrectIncorrect - Question 18 of 50
18. Question
1 points18which of the following are the actions of Sulfonylureas
I stimulate insulin release from pancreatic beta cells
II enhance peripheral sensitivity to insulin
III decreasing hepatic gluconeogenesis productionCorrectIncorrect - Question 19 of 50
19. Question
1 points19 which of the following are the Meglitinide derivatives
I repaglinide
II nateglinide
III tolbutamideCorrectIncorrect - Question 20 of 50
20. Question
1 points20 which of the following are true about the Meglitinide derivatives
I shorter-acting insulin secretagogues
II preprandialy dosed
III long-acting insulin secretagoguesCorrectIncorrect - Question 21 of 50
21. Question
1 points21 which of the following are true about the Meglitinide derivatives
I risk for inducing weight gain as sulfonylureas
II carry less risk for hypoglycemia.
III carry more risk for hypoglycemia.CorrectIncorrect - Question 22 of 50
22. Question
1 points22 which of the following are true about Alpha-glucosidase inhibitors
I delay sugar absorption
II prevent postprandial glucose surges
III flatulence greatly limits their useCorrectIncorrect - Question 23 of 50
23. Question
1 points23 which of the following are true about Thiazolidinediones
I act as insulin sensitizers
II require the presence of insulin to work
III slow the progression of diabetes (particularly in early disease)CorrectIncorrect - Question 24 of 50
24. Question
1 points24 which of the following are the adverse reaction of Thiazolidinediones
I weight gain
II Fluid retention
III bladder cancerCorrectIncorrect - Question 25 of 50
25. Question
1 points25 which of the following are Glucagonlike peptide–1 agonists
I exenatide, liraglutide
II liraglutide, albiglutide
III albiglutide, dulaglutideCorrectIncorrect - Question 26 of 50
26. Question
1 points26 which of the following are the actions of Glucagonlike peptide–1 agonists
I stimulate glucose-dependent insulin release
II reduce glucagon
III slow gastric emptyingCorrectIncorrect - Question 27 of 50
27. Question
1 points27 which of the following are true about exenatide
I Exenatide has greater ease of titration than does insulin
II requires twice-daily injections
III long-acting exenatide formulation that is given once weekly (Bydureon) is availableCorrectIncorrect - Question 28 of 50
28. Question
1 points28 which of the following are Dipeptidyl peptidase IV inhibitors
I sitagliptin
II saxagliptin
III linagliptinCorrectIncorrect - Question 29 of 50
29. Question
1 points29 which of the following statement are true about Dipeptidyl peptidase IV inhibitors
I prolong the action of incretin hormones
II given once daily and are weight neutral.
III cause weight gainCorrectIncorrect - Question 30 of 50
30. Question
1 points30 which of the following are true about linagliptin
I predominantly nonrenal excreted
II low risk of drug-drug interaction
III safe to use in patients with renal insufficiency.CorrectIncorrect - Question 31 of 50
31. Question
1 points31 which of the following are Selective sodium-glucose transporter-2 inhibitors
I Canagliflozin
II dapagliflozin
III empagliflozinCorrectIncorrect - Question 32 of 50
32. Question
1 points32 which of the following drugs causes increased urinary glucose excretion
I Canagliflozin
II sitagliptin
III exenatideCorrectIncorrect - Question 33 of 50
33. Question
1 points33 which of the following is true about Canagliflozin
I lowers the renal glucose threshold
II Dosage adjustments are required in patients with renal impairment
III should not be used if eGFR is < 60 mL/min/1.73 mCorrectIncorrect - Question 34 of 50
34. Question
1 points34 Amylinomimetics actions include
I delays gastric emptying
II decreases postprandial glucagon release
III lowers the renal glucose thresholdCorrectIncorrect - Question 35 of 50
35. Question
1 points35 which of the following statements are true about antidiabetic medications
I Metformin decreased LDL cholesterol levels
II Unfavorable effects on weight were greater with TZDs and sulfonylureas
III Risk of heart failure was higher with TZDs than with sulfonylureasCorrectIncorrect - Question 36 of 50
36. Question
1 points36 which of the following statements are true about Metformin
I Absence of weight gain or hypoglycemia
II should take during or after meals to reduce gastrointestinal [GI] side effects
III decrease the risk of dementia associated with type 2 diabetes.CorrectIncorrect - Question 37 of 50
37. Question
1 points37 which of the following considered in Dual-drug therapy with metformin
I DPP-4 inhibitor if both postprandial and fasting glucose levels are elevated
II GLP-1 agonist if postprandial glucose levels are strongly elevated
III TZD if the patient has metabolic syndromeCorrectIncorrect - Question 38 of 50
38. Question
1 points38 which of the following drugs are used in patients with obesity
I metformin
II sulphonyl urea
III TZDCorrectIncorrect - Question 39 of 50
39. Question
1 points39 which of the following are long acting insulins
I glargine
II detemir
III aspartCorrectIncorrect - Question 40 of 50
40. Question
1 points40 rapid-acting insulin includes
I aspart
II glulisine
III lisproCorrectIncorrect - Question 41 of 50
41. Question
1 points41 lipodystrophy is a condition associated with the use of which of the drugs
I insulin
II metformin
III sulfonyl ureaCorrectIncorrect - Question 42 of 50
42. Question
1 points42 insulin is likely to be needed by most patients with:
I rapid onset of symptoms
II substantial loss of weight
III ketonuriaCorrectIncorrect - Question 43 of 50
43. Question
1 points43 which of the following are true about the use of insulin
I Insulin is required by almost all children with diabetes.
II insulin is also needed for type 2 diabetes when other methods have failed
III insulin is also needed in pregnant women with type 1 diabetes when other methods have failedCorrectIncorrect - Question 44 of 50
44. Question
1 points44 which of the following are the characteristics of insulin lispro
I short duration
II rapid onset of action
III soluble insulinCorrectIncorrect - Question 45 of 50
45. Question
1 points45 rapid-acting insulin analogues includes
I insulin aspart, insulin glulisine
II insulin glulisine, and insulin lispro
III insulin lispro and isophane insulinCorrectIncorrect - Question 46 of 50
46. Question
1 points46. isophane insulin characteristics includes
I short duration
II intermediate action
III rapid-acting insulinCorrectIncorrect - Question 47 of 50
47. Question
1 points47 insulin whose action is slower in onset and lasts for long periods includes
I protamine zinc insulin
II isophane insulin
III insulin detemir, and insulin glargineCorrectIncorrect - Question 48 of 50
48. Question
1 points48 protamine zinc insulin characteristics includes
I slower in onset
II short duration
III intermediate actionCorrectIncorrect - Question 49 of 50
49. Question
1 points49 Insulin requirements may be increased by
I infection, stress,
II accidental or surgical trauma
III puberty.CorrectIncorrect - Question 50 of 50
50. Question
1 points50 Insulin requirements may be decreased by
I Addison’s disease
II hypopituitarism
III coeliac diseaseCorrectIncorrect